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Principal Systems Engineer – Clinical Computation Platform

Amgen

Principal Systems Engineer – Clinical Computation Platform

full-timePosted: Jul 29, 2026Updated: Aug 28, 2026India - Hyderabad

Job Description

Career CategoryClinicalJob DescriptionABOUT AMGEN Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today. ABOUT THE ROLE Role Description: The role is responsible for the design, integration, and management of complex systems that encompass both hardware and software components into the organization’s cloud infrastructure. This individual will be responsible for all activities related to handling and supporting the Business and platforms including system administration, as well as incorporating new technologies under the challenge of a sophisticated and constantly evolving technology landscape. This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements. Roles & Responsibilities: Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered Develop and design systems architecture, ensuring that it meets both current and future needs of the organization Integrate hardware and software components into a cohesive system that meets functional and performance requirements Perform system testing and validation to ensure all components function correctly and efficiently Optimize system performance and troubleshoot any issues that arise during system operation Create and maintain comprehensive documentation of systems design, configurations, and procedures Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems Monitor and maintain systems to ensure they continue to operate effectively and efficiently Implement automation tools and processes to improve the efficiency and reliability of the system Conduct training and workshops for business teams to share best practices in the industry. Basic Qualifications and Experience: Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field Functional Skills: Must-Have Skills: Experience in cloud platforms including AWS Experience with container technologies like Docker and Kubernetes Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements Experience with translating business requirements to technical requirements and recommend solutions for automation Proficiency in programming languages including R, Python Experience and strong knowledge of POSIT Tools and Services Strong understanding of software development methodologies, including Agile and Scrum Good-to-Have Skills: Experience with DevOps tools and practices Strong understanding of systems engineering processes and methodologies Experience with systems integration and validation Knowledge of Clinical Development domain Professional Certifications: Scaled Agile Framework (SAFe) for Teams (preferred) Soft Skills: Excellent analytical and troubleshooting skills Strong verbal and written communication skills Ability to work effectively with global, virtual teams High degree of initiative and self-motivation Ability to manage multiple priorities successfully Team-oriented, with a focus on achieving team goals Strong presentation and public speaking skills Shift Information: This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements. EQUAL OPPORTUNITY STATEMENT Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. .

Locations

  • India - Hyderabad

Skills Required

  • Computer Scienceintermediate
  • DevOps toolsintermediate
  • systems integrationintermediate
  • Clinical Development domainintermediate

Required Qualifications

  • Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field (experience, 17 years)
  • Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field (experience, 17 years)
  • Functional Skills: (experience)

Preferred Qualifications

  • Experience with DevOps tools and practices (experience)
  • Experience with DevOps tools and practices (experience)
  • Strong understanding of systems engineering processes and methodologies (experience)
  • Strong understanding of systems engineering processes and methodologies (experience)
  • Experience with systems integration and validation (experience)
  • Experience with systems integration and validation (experience)
  • Knowledge of Clinical Development domain (experience)
  • Knowledge of Clinical Development domain (experience)
  • Professional Certifications: (certification)
  • Scaled Agile Framework (SAFe) for Teams (preferred) (experience)
  • Excellent analytical and troubleshooting skills (experience)
  • Excellent analytical and troubleshooting skills (experience)
  • Strong verbal and written communication skills (experience)
  • Strong verbal and written communication skills (experience)
  • Ability to work effectively with global, virtual teams (experience)
  • Ability to work effectively with global, virtual teams (experience)
  • High degree of initiative and self-motivation (degree)
  • High degree of initiative and self-motivation (degree)
  • Ability to manage multiple priorities successfully (experience)
  • Ability to manage multiple priorities successfully (experience)
  • Team-oriented, with a focus on achieving team goals (experience)
  • Team-oriented, with a focus on achieving team goals (experience)
  • Strong presentation and public speaking skills (experience)
  • Strong presentation and public speaking skills (experience)
  • Shift Information: (experience)
  • This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements. (experience)

Responsibilities

  • Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization
  • Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization
  • Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines
  • Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines
  • Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered
  • Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered
  • Develop and design systems architecture, ensuring that it meets both current and future needs of the organization
  • Develop and design systems architecture, ensuring that it meets both current and future needs of the organization
  • Integrate hardware and software components into a cohesive system that meets functional and performance requirements
  • Integrate hardware and software components into a cohesive system that meets functional and performance requirements
  • Perform system testing and validation to ensure all components function correctly and efficiently
  • Perform system testing and validation to ensure all components function correctly and efficiently
  • Optimize system performance and troubleshoot any issues that arise during system operation
  • Optimize system performance and troubleshoot any issues that arise during system operation
  • Create and maintain comprehensive documentation of systems design, configurations, and procedures
  • Create and maintain comprehensive documentation of systems design, configurations, and procedures
  • Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems
  • Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems
  • Monitor and maintain systems to ensure they continue to operate effectively and efficiently
  • Monitor and maintain systems to ensure they continue to operate effectively and efficiently
  • Implement automation tools and processes to improve the efficiency and reliability of the system
  • Implement automation tools and processes to improve the efficiency and reliability of the system
  • Conduct training and workshops for business teams to share best practices in the industry.
  • Conduct training and workshops for business teams to share best practices in the industry.

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