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Upstream/AME Manufacturing Manager, Nights

Amgen

Upstream/AME Manufacturing Manager, Nights

full-timePosted: Aug 25, 2026Updated: Aug 28, 2026US - Rhode Island - West Greenwich

Job Description

Career CategoryOperationsJob DescriptionJoin Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Upstream/AME Manufacturing Manager, NightsWhat you will doLet’s do this! Let’s change the world! In this vital role you will be responsible for leading a team in production operations on the manufacturing floor including cell culture operations in our flexible manufacturing facility as well as leadership of the Agile Manufacturing Excellence team for this shift, which will operate flexibly across all areas of both AR30 and AR5. This role will leverage continuous improvement, transformative approaches and innovation to drive reliability, efficiency, agility and differentiation. The manager will champion a safe and compliant production environment through structured on floor presence. This position is for the night shift. The shift pattern will be 7PM-7AM structure with a rotation covering 7 days per week.Responsibiliteis:Create a culture of safety, quality, and continuous improvementOversee right first time on the floor execution of the production planDeliver strong business resultsDevelop a high-performing team, build technical and leadership capabilities within the organization to meet current and future business needsEnsure the right people and resources are in place and optimally allocated to achieve resultsCreate an environment that fosters accountability, agility, innovation, continuous improvement, learning and knowledge-sharingEnsure effective decision-makingOversee manufacturing validation activitiesResponsible for overseeing new technology implementation in manufacturingAttract, develop and retain diverse talentConduct short and long-range talent planning to ensure readiness of talent to execute future organizational objectivesWork across functions to build organization and individual capabilitiesDevelop strong relationships with staff members, provide open and clear feedback to improve individual and team performanceWhat we expect of youWe are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a motivated individual with these qualifications.Basic Qualifications:High school diploma / GED and 12 years of Manufacturing and Operations experience ORAssociate’s degree and 10 years of Manufacturing and Operations experience ORBachelor’s degree and 5 years of Manufacturing and Operations experience ORMaster’s degree and 3 years of Manufacturing and Operations experience ORDoctorate degreeIn addition to meeting at least one of the above requirements, you must have experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced abovePreferred Qualifications:Bachelor’s degree in Life Sciences or EngineeringKnowledge and experience within a cGMP or other highly regulated environment including a basic understanding of technical elements across engineering, biological or chemical processingAbility to adapt to shifting priorities, remove barriers and provide support where neededLead with clarity, communicate transparently and build trusting relationshipsStrong leadership and teambuilding skills (coaching, mentoring, counseling)Experience with Lean Principles and continuous improvementExperience with performance management including conflict resolution and performance reviewsAnalytical problem-solving skillsThorough understanding of regulatory requirementsAbility to be flexible and manage changeExcellent verbal and written communication (technical) skillsWhat you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accountsA discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plansFlexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.Apply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.SponsorshipSponsorship for this role is not guaranteed.As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation..Salary Range106,148.00USD -143,612.00 USD

Locations

  • US - Rhode Island - West Greenwich

Skills Required

  • Lean Principlesintermediate
  • performance management including conflict resolutionintermediate

Required Qualifications

  • High school diploma / GED and 12 years of Manufacturing and Operations experience OR (experience, 12 years)
  • Associate’s degree and 10 years of Manufacturing and Operations experience OR (experience, 10 years)
  • Bachelor’s degree and 5 years of Manufacturing and Operations experience OR (experience, 5 years)
  • Master’s degree and 3 years of Manufacturing and Operations experience OR (experience, 3 years)
  • Doctorate degree (degree)
  • In addition to meeting at least one of the above requirements, you must have experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above (experience)
  • High school diploma / GED and 12 years of Manufacturing and Operations experience OR (experience, 12 years)
  • Associate’s degree and 10 years of Manufacturing and Operations experience OR (experience, 10 years)
  • Bachelor’s degree and 5 years of Manufacturing and Operations experience OR (experience, 5 years)
  • Master’s degree and 3 years of Manufacturing and Operations experience OR (experience, 3 years)
  • Doctorate degree (degree)
  • In addition to meeting at least one of the above requirements, you must have experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above (experience)
  • Ability to be flexible and manage change (experience)
  • Excellent verbal and written communication (technical) skills (experience)

Preferred Qualifications

  • Bachelor’s degree in Life Sciences or Engineering (degree in life sciences or engineering)
  • Knowledge and experience within a cGMP or other highly regulated environment including a basic understanding of technical elements across engineering, biological or chemical processing (experience)
  • Ability to adapt to shifting priorities, remove barriers and provide support where needed (experience)
  • Lead with clarity, communicate transparently and build trusting relationships (experience)
  • Strong leadership and teambuilding skills (coaching, mentoring, counseling) (experience)
  • Experience with Lean Principles and continuous improvement (experience)
  • Experience with performance management including conflict resolution and performance reviews (experience)
  • Analytical problem-solving skills (experience)
  • Thorough understanding of regulatory requirements (experience)
  • Ability to be flexible and manage change (experience)
  • Excellent verbal and written communication (technical) skills (experience)
  • Bachelor’s degree in Life Sciences or Engineering (degree in life sciences or engineering)
  • Knowledge and experience within a cGMP or other highly regulated environment including a basic understanding of technical elements across engineering, biological or chemical processing (experience)
  • Ability to adapt to shifting priorities, remove barriers and provide support where needed (experience)
  • Lead with clarity, communicate transparently and build trusting relationships (experience)
  • Strong leadership and teambuilding skills (coaching, mentoring, counseling) (experience)
  • Experience with Lean Principles and continuous improvement (experience)
  • Experience with performance management including conflict resolution and performance reviews (experience)
  • Analytical problem-solving skills (experience)

Responsibilities

  • Create a culture of safety, quality, and continuous improvement
  • Oversee right first time on the floor execution of the production plan
  • Deliver strong business results
  • Develop a high-performing team, build technical and leadership capabilities within the organization to meet current and future business needs
  • Ensure the right people and resources are in place and optimally allocated to achieve results
  • Create an environment that fosters accountability, agility, innovation, continuous improvement, learning and knowledge-sharing
  • Ensure effective decision-making
  • Oversee manufacturing validation activities
  • Responsible for overseeing new technology implementation in manufacturing
  • Attract, develop and retain diverse talent
  • Conduct short and long-range talent planning to ensure readiness of talent to execute future organizational objectives
  • Work across functions to build organization and individual capabilities
  • Develop strong relationships with staff members, provide open and clear feedback to improve individual and team performance
  • Create a culture of safety, quality, and continuous improvement
  • Oversee right first time on the floor execution of the production plan
  • Deliver strong business results
  • Develop a high-performing team, build technical and leadership capabilities within the organization to meet current and future business needs
  • Ensure the right people and resources are in place and optimally allocated to achieve results
  • Create an environment that fosters accountability, agility, innovation, continuous improvement, learning and knowledge-sharing
  • Ensure effective decision-making
  • Oversee manufacturing validation activities
  • Responsible for overseeing new technology implementation in manufacturing
  • Attract, develop and retain diverse talent
  • Conduct short and long-range talent planning to ensure readiness of talent to execute future organizational objectives
  • Work across functions to build organization and individual capabilities
  • Develop strong relationships with staff members, provide open and clear feedback to improve individual and team performance

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