Company Overview: Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases. Position Overview: The VP, Clinical Development will serve as the medical lead for base editing gene therapies in our metabolic franchise and represent Beam both internally and externally. The position will report to the EVP, Head of Clinical Development. The candidate will develop the vision, mission, outline the strategies, establish the priorities, create alignment, and have full accountability for Beam’s clinical metabolic efforts. The VP of Clinical Development will oversee implementation and maintenance of all metabolic internal clinical development programs and will also have the strategic view and excellence in execution to continue to grow the strength and scope of the internal pipeline, in addition to participating in potential business development opportunities, including additional acquisitions. Importantly, the role will be highly visible requiring effectively communicating the Beam Vision and Values in metabolic diseases to other functional groups and to key external stakeholders. Responsibilities: Lead efforts to develop, refine a vision for the Beam metabolic franchise strategy in a collaborative environment. Develop and implement near- and long-term goals and objectives that are aligned with the strategic vision. In line with corporate objectives, provide relevant medical counsel and scientific guidance to all teams across Beam that are involved in metabolic therapeutic-related activities. Work with cross-functional teams to develop integrated clinical/regulatory strategies for key initiatives to support the successful registration and commercialization of products for the metabolic therapeutic area. Support cross-functional metabolic teams. Design clinical development plans, target-product profiles and protocols that are aligned to support the integrated clinical/regulatory/commercial strategies for the therapeutic area. Provide strategic and medical oversite of planned and ongoing clinical trials. Ensure high quality clinical development standards with respect to clinical study design, conduct, and oversight of patient safety. Support the Research & Development Leadership Team as well as Business Development as it relates to metabolic research and clinical development activities. Work closely with research teams to develop next gen therapeutic programs. Attend and help prepare material for medical conferences, Regulatory Agency meetings, Advisory Boards and other relevant clinical events as required. Manage and mentor multiple physicians and clinical scientist direct reports. Qualifications: MD, DO or equivalent ex-US medical degree with 15+ years’ experience, 10+ years clinical development experience in industry is a must. Final level and scope of role will be commensurate with experience. Clinical or drug development experience in metabolic diseases and/or rare disease is desirable. Must have previous patient care experience. Demonstrated ability to successfully execute clinical development projects across all phases of drug discovery. Proven track record of successful interactions with regulatory authorities. Demonstrated ability to lead and influence experienced professionals. Experience working with commercial strategies is desirable. Ability to lead in a fast-changing environment. Broad knowledge and exposure across all R&D functions. Deep understanding of clinical/pre-clinical pharmaceutical development. Strategic thinker with strong execution skills. Effective communicator. Location Requirement: This is a hybrid role; however, this role requires that the candidate(s) live within a reasonable commuting distance to be on site in our Cambridge location several times per week. The salary range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, education, scope of job, internal comparisons, and market data.Beam Pay Range$310,000—$400,000 USD