Sr. Manager, Biomarker Research
Merck
Sr. Manager, Biomarker Research
Job Description
Job DescriptionBiomarker lead, Senior Manager/Associate DirectorLocation: Shanghai, BeijingWe are seeking a highly motivated scientist to drive clinical biomarker strategy and provide scientific expertise on biomarker research/disease mechanism to support internal and external collaboration clinical development programs across therapeutic areas in China. Key responsibilities:He/She will be collaborating closely with cross-functional teams to systematically develop and implement biomarker strategy in clinical development programs in China.Provide scientific and/or technical input to China innovative collaboration center (MCICC) asset development teams on biomarker-related elements of study trial design and conduct, incorporating biomarkers into clinical protocols.Liaises with China clinical research team, China clinical pharmacology team, China Biomarker Operation lead, China biomarker technical experts, and external partners to ensure alignment, and efficient implementation of key deliverables for biomarker. Work closely with China Biostatistics and Research Decision Sciences (BARDS) team, and/or China Bioinformatics team in analyzing, interpreting and presenting results from biomarker analyses. Represents biomarker related aspects internally with China/global teams, and externally in meetings with authorities and external key opinion leaders.Builds and maintain network with academic institutions and/or industry in biomarker area in China.QualificationsRequired:Ph.D. in biology, pharmacology or a related life science field with 5+ years of pharmaceutical/preclinical research experience.Track record of biomarker strategy development and implementation in FIH, Ph1/2 studies.Broad knowledge of technical platforms that include IHC, immunoassay, PCR, and NGS.Understanding of drug discovery & developmentProficient in gaining emerging knowledge for various TAs/assets and agile in working in a fast-paced environment.Demonstrate exceptional written and verbal communication skills in English and Chinese.Experience with a matrix environment and ability to effectively collaborate with colleagues from a wide range of disciplines.Preferred:Experience in early clinical research, including oncology or immunology.Deep understanding of biomarker science and clinical application.Record of publishing in high profile scientific journals.Understanding of clinical biomarker operations and experience with HGRAC application is valued.Required Skills: Accountability, Accountability, Assay Development, Biochemical Assays, Biochemistry, Bioinformatics, Biomarkers, Cell Biology, Clinical Development, Clinical Research, Cross-Functional Collaboration, Cytometry, Cytopathology, Detail-Oriented, Drug Discovery Process, Ethical Compliance, High-Throughput Screening, Immunoassays, Immunochemistry, Immunology, Mammalian Cell Culture, Molecular Biology, Oncology, Oral Communications, Professional Networking {+ 4 more}Preferred Skills: Current Employees apply HERECurrent Contingent Workers apply HERESearch Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: RegularRelocation:No relocationVISA Sponsorship:NoTravel Requirements:No Travel RequiredFlexible Work Arrangements:Not ApplicableShift:Not IndicatedValid Driving License:NoHazardous Material(s):noJob Posting End Date:10/31/2026*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Locations
- CHN - Shanghai - Shanghai (Tower A)
Skills Required
- technical platforms that include IHCintermediate
- gaining emerging knowledge for various TAs/assetsintermediate
- matrix environmentintermediate
- early clinical researchintermediate
- HGRAC application is valuedintermediate
Required Qualifications
- Ph.D. in biology, pharmacology or a related life science field with 5+ years of pharmaceutical/preclinical research experience. (experience, 5 years)
- Track record of biomarker strategy development and implementation in FIH, Ph1/2 studies. (experience)
- Broad knowledge of technical platforms that include IHC, immunoassay, PCR, and NGS. (experience)
- Understanding of drug discovery & development (experience)
- Proficient in gaining emerging knowledge for various TAs/assets and agile in working in a fast-paced environment. (experience)
- Demonstrate exceptional written and verbal communication skills in English and Chinese. (experience)
- Experience with a matrix environment and ability to effectively collaborate with colleagues from a wide range of disciplines. (experience)
- Ph.D. in biology, pharmacology or a related life science field with 5+ years of pharmaceutical/preclinical research experience. (experience, 5 years)
- Track record of biomarker strategy development and implementation in FIH, Ph1/2 studies. (experience)
- Broad knowledge of technical platforms that include IHC, immunoassay, PCR, and NGS. (experience)
- Understanding of drug discovery & development (experience)
- Proficient in gaining emerging knowledge for various TAs/assets and agile in working in a fast-paced environment. (experience)
- Demonstrate exceptional written and verbal communication skills in English and Chinese. (experience)
- Experience with a matrix environment and ability to effectively collaborate with colleagues from a wide range of disciplines. (experience)
Preferred Qualifications
- Experience in early clinical research, including oncology or immunology. (experience)
- Deep understanding of biomarker science and clinical application. (experience)
- Experience in early clinical research, including oncology or immunology. (experience)
- Deep understanding of biomarker science and clinical application. (experience)
- Record of publishing in high profile scientific journals. (experience)
- Understanding of clinical biomarker operations and experience with HGRAC application is valued. (experience)
- Record of publishing in high profile scientific journals. (experience)
- Understanding of clinical biomarker operations and experience with HGRAC application is valued. (experience)
- Current Employees apply HERE (experience)
- Current Contingent Workers apply HERE (experience)
Responsibilities
- He/She will be collaborating closely with cross-functional teams to systematically develop and implement biomarker strategy in clinical development programs in China.
- Provide scientific and/or technical input to China innovative collaboration center (MCICC) asset development teams on biomarker-related elements of study trial design and conduct, incorporating biomarkers into clinical protocols.
- Liaises with China clinical research team, China clinical pharmacology team, China Biomarker Operation lead, China biomarker technical experts, and external partners to ensure alignment, and efficient implementation of key deliverables for biomarker.
- Work closely with China Biostatistics and Research Decision Sciences (BARDS) team, and/or China Bioinformatics team in analyzing, interpreting and presenting results from biomarker analyses.
- Represents biomarker related aspects internally with China/global teams, and externally in meetings with authorities and external key opinion leaders.
- Builds and maintain network with academic institutions and/or industry in biomarker area in China.
- He/She will be collaborating closely with cross-functional teams to systematically develop and implement biomarker strategy in clinical development programs in China.
- Provide scientific and/or technical input to China innovative collaboration center (MCICC) asset development teams on biomarker-related elements of study trial design and conduct, incorporating biomarkers into clinical protocols.
- Liaises with China clinical research team, China clinical pharmacology team, China Biomarker Operation lead, China biomarker technical experts, and external partners to ensure alignment, and efficient implementation of key deliverables for biomarker.
- Work closely with China Biostatistics and Research Decision Sciences (BARDS) team, and/or China Bioinformatics team in analyzing, interpreting and presenting results from biomarker analyses.
- Represents biomarker related aspects internally with China/global teams, and externally in meetings with authorities and external key opinion leaders.
- Builds and maintain network with academic institutions and/or industry in biomarker area in China.
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