Who We Are:Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)About the Role:Responsible for devising the medicinal chemistry strategy on projects. Leads or co-leads multidisciplinary project teams to advance discovery programs to key milestones. Provides expertise in medicinal chemistry principles, complex small molecule synthesis, purification, and data analysis across multiple projects and outside of direct team. Supervises and mentors both internal direct reports and external CROs towards hypothesis driven chemistry strategies as well as mentoring and influencing chemistry outside of direct group. Monitors and evaluates completion of tasks and projects._Your Contributions (include, but are not limited to):Leads projects and initiatives in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification and novel chemistryDistills complicated, multidimensional data to clear hypotheses and new experimental directionsImports new principles/concepts to develop useful new experimental approachesResearches external intellectual property relevant to project(s) and areas of pursuit and collaborates with internal IP team to plan patent strategyContributes substantively to patent and publication preparation and planningResponsible for designing, planning, and conducting synthesis of analogs and analog librariesParticipates in a multidisciplinary team committed to the continuous improvement of the lead optimization process as well as the expeditious identification and progression of development compounds as well communicating results to the project or program team, or to managementPlans and manages projects. Represents Medicinal Chemistry on cross-functional teams and may lead cross-functional teams. Maintains accountability for deliverables and progress for projects as well as development of internal teamsIndependently designs, plans and executes activities towards the goals of one or more Medicinal Chemistry projects to support lead generation through pre-clinical activitiesCreates and implements novel ideas in Medicinal ChemistryProvides effective supervision of lab work and lab personnel and guidance for their professional development as well as ensuring safe laboratory practicesBuilds and enhances internal and external professional relationships and collaborationsOther duties as assignedRequirements:BS/BA in Chemistry AND 12+ years of experience in medicinal chemistry and drug discovery ORMS/MA in Chemistry AND 10+ years of experience in medicinal chemistry and drug discovery ORPhD or equivalent in Organic Chemistry or Medicinal Chemistry AND 8+ years of relevant experience in medicinal chemistry and drug discoveryAdvanced knowledge of most or all of the following: complex organic synthesis, parallel synthesis, data analysis, lab automation, and purification in the optimization of lead compoundsThorough understanding of medicinal chemistry and multi parameter optimization of drug-like compounds and a well-developed understanding of current literatureExcellent interpersonal skills with strong oral and written communication abilitiesExcellent laboratory and productivity skills, and the ability to lead and mentor small teams of chemists in these skillsDemonstration of strong cross-functional understanding related to drug development and the identification of high quality candidate compoundsExcellent communication skills and ability to collaborate in a matrix environment are requiredStrong track record of innovation demonstrated through patents and publications and development candidates is necessaryAssimilates data and research findings outside of Neurocrine for application to new scientific projects and ideasMaintains broad knowledge of scientific principles and theories and possesses intellectual mastery of multiple scientific areasApplies understanding of the team's place in the larger organization, and discusses changes, progress, and issues as they relate to other areasSees broader picture, impact on multiple programs, teams and/or departments and the companyAbility to work as part of and lead multiple teamsExcellent project management, strong project leadership skills, typically leads small team and/or indirect teamsExcellent computer, presentation, communications, problem-solving and analytical thinking skillsAbility to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency#LI-LS1Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description._The annual base salary we reasonably expect to pay is $156,900.00-$214,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.