Who We Are:Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)About the Role:Responsible for leading and advancing enterprise portfolio strategy, optimization, analytics, and resource planning capabilities across Neurocrine's research and development portfolio. Serves as a strategic advisor to executive leadership, providing data-driven insights and recommendations that support portfolio prioritization, investment decisions, resource allocation, and long-range planning. Leads highly complex portfolio planning and analytics activities with significant organizational impact, risk, and complexity. Develops and implements portfolio optimization frameworks, forecasting models, scenario analyses, and decision-support capabilities that enable effective governance and maximize portfolio value. Partners closely with R&D, Finance, Program Management, Business Development, and Executive Leadership to drive strategic decision-making across discovery, development, and lifecycle programs. Serves as the enterprise subject matter expert for portfolio planning systems, portfolio analytics, and resource optimization methodologies while driving continuous improvement of portfolio management capabilities across the organization._Your Contributions (include, but are not limited to):Leads development and execution of enterprise portfolio strategy, prioritization, and optimization frameworks aligned with corporate and R&D objectivesOwns and manages Neurocrine's multi-year compound flow model, including risk-adjusted and non-risk-adjusted portfolio scenarios across therapeutic areas and development stagesDevelops and maintains transition probability models across development stages and modalities to support portfolio forecasting, investment planning, and strategic decision-makingLeads executive-level portfolio prioritization and trade-off discussions, translating complex portfolio data into actionable recommendations that support portfolio investment and resource allocation decisionsEvaluates portfolio opportunities, risks, development scenarios, and investment alternatives to maximize overall portfolio valueDesigns and oversees quantitative models supporting portfolio forecasting, probability of success analyses, development timelines, resource planning, and investment decision-makingDevelops scenario analyses evaluating the impact of adding, removing, accelerating, delaying, or restructuring portfolio programsAnalyzes pipeline progression, development productivity, attrition rates, cycle times, and key portfolio performance indicators to support strategic planning and governance discussionsLeads enterprise resource planning and capacity forecasting activities across functions, therapeutic areas, and development stages.Partners with Finance, Program Management, and functional leaders to align portfolio objectives with organizational capacity, budgetary constraints, and long-range planning assumptionsDevelops portfolio-level financial models supporting annual operating plans, investment prioritization, resource planning, and budget forecasting activitiesIdentifies resource constraints, operational risks, and strategic opportunities and develops recommendations to optimize portfolio executionServes as business owner and subject matter expert for portfolio planning systems, including Planisware and related portfolio management platformsEstablishes portfolio data standards, governance processes, and analytics best practices to support high-quality portfolio decision-makingDrives implementation and continuous improvement of portfolio analytics tools, systems, reporting capabilities, and governance processesLeads benchmarking initiatives evaluating development timelines, costs, resource models, productivity metrics, and industry best practicesLeverages AI-enabled tools, external data sources, and advanced analytics methodologies to enhance portfolio insights, forecasting accuracy, and competitive benchmarking capabilitiesDevelops executive dashboards, portfolio reviews, governance materials, and Board-level presentationsProvides analytical support for business development evaluations, external innovation opportunities, and strategic investment assessmentsLeads cross-functional portfolio planning processes and governance forums to drive alignment, transparency, accountability, and execution excellenceServes as a trusted advisor to executive leadership on portfolio strategy, prioritization, resource allocation, and long-term planning decisionsProvides leadership, coaching, and mentoring to team members and cross-functional partnersOther duties as assignedRequirements:BS/BA degree in Life Sciences, Business, Finance, Engineering, Data Analytics, Operations Research, or related discipline and 14+ years of relevant pharmaceutical, biotechnology, healthcare, consulting, portfolio management, strategy, or related industry experience ORMaster's degree in a related discipline and 12+ years of relevant experience ORPhD, PharmD, MBA, or other advanced degree and 10+ years of relevant experienceDeep understanding of pharmaceutical drug development across discovery, preclinical, clinical, regulatory, and commercialization stagesSignificant experience managing multi-year compound flow models and portfolio forecasting methodologiesExpert knowledge of portfolio strategy, portfolio management, resource planning, and investment decision-making frameworksExtensive experience supporting portfolio governance processes and executive-level decision-makingAdvanced experience with Planisware or comparable portfolio management and planning platformsExperience implementing, managing, or optimizing portfolio planning systems, analytics capabilities, and governance processesStrong understanding of portfolio valuation, probability of success modeling, scenario planning, forecasting techniques, and portfolio optimization methodologiesExperience leading enterprise portfolio planning and prioritization processes across complex, multi-asset development portfoliosDemonstrated success influencing senior leaders and facilitating executive-level portfolio prioritization, investment, and resource allocation decisionsExperience developing multi-year portfolio strategies and long-range planning scenarios aligned with organizational objectivesExperience supporting executive governance committees, portfolio review forums, and strategic planning processesStrong understanding of R&D financial planning, budgeting, forecasting, and resource allocation processesExperience leading portfolio benchmarking and competitive operational analysesExperience preparing executive leadership and Board-level presentations and materialsFamiliarity with AI-enabled analytics tools, advanced modeling techniques, and external benchmarking resources preferredAbility to evaluate portfolio risks and opportunities and translate findings into strategic recommendations that influence organizational strategy and investment decisionsStrong strategic thinking, business acumen, and ability to integrate scientific, operational, financial, and portfolio considerations into decision-makingExceptional communication, influence, stakeholder management, and relationship-building skillsDemonstrated ability to communicate complex analyses and strategic recommendations to diverse audiences, including senior executivesStrong analytical, critical thinking, problem-solving, and decision-making capabilitiesProven ability to lead through influence and achieve results within highly matrixed organizationsDemonstrated ability to develop innovative solutions to complex business challenges with significant organizational impactStrong planning, prioritization, organizational, and project leadership skillAbility to manage multiple competing priorities in a dynamic and evolving portfolio environmentDemonstrated ability to build partnerships and align stakeholders across functions and organizational levelsStrong attention to detail while maintaining an enterprise-wide perspectiveAbility to mentor, coach, and develop others while fostering a culture of accountability and continuous improvement.Advanced proficiency with portfolio management, business planning, analytics, forecasting, and reporting tools#LI-CL1Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description._The annual base salary we reasonably expect to pay is $226,500.00-$309,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.