Build our future together:At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Scientist to join our team developing therapies for hearing loss and vestibular disorders. In this role, you will independently lead research projects and drive the development of novel therapies for inner ear disorders, while collaborating with a cross-functional team to advance translationally relevant studies.This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.When & where:Location: Tarrytown, NYWork model/flexibility: OnsiteDiscover your role:Lead the design of rigorous experiments to address core questions in hearing biology that drive drug discovery and preclinical programsDevelop and characterize novel animal models to understand mechanisms of hearing loss and evaluate novel therapeuticsDesign and execute in vivo and in vitro functional assays to understand syndromic and non-syndromic hearing lossWork cross-functionally with a team to develop translationally relevant studiesAnalyze and evaluate data with rigor, presenting findings internally and externallyDraft and review protocols and articles for publication independentlyMotivate, develop, and supervise junior scientists, research associates, and other traineesThrive in a dynamic, fast-paced environment, adapting readily to shifting prioritiesThis role requires:Ph.D. with a strong record of innovation and publication, plus 5+ years of relevant experienceProven expertise in drug developmentStrong ability to work both independently and in a team, communicating effectively across all levelsResilience in overcoming challenges and a rigorous approach to scientific workPreferred: managerial experiencePreferred: in vivo experimental experiencePreferred: strong understanding of human and mouse genetics and/or auditory physiologyDoes this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.For jobs in Canada: this posting is for an existing position.Salary Range (annually)$128,600.00 - $210,000.00