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Sr. Staff Database Architect

Thermo Fisher Scientific

Sr. Staff Database Architect

full-timePosted: Aug 18, 2026Updated: Sep 1, 2026USA, Indiana, Remote (Remote)

Job Description

Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionJob Summary We are seeking a Database Architect to design and manage secure, scalable, and compliant database systems for our healthcare SaaS platform. This role requires expertise in handling sensitive data, including PII/PPI and PHI, while ensuring compliance with healthcare regulations and delivering high-performance, multi-tenant solutions. Key Responsibilities Design and implement secure, scalable, multi-tenant database architectures for healthcare SaaS applications Develop data models and storage solutions for sensitive healthcare data (PHI, PII/PPI) Ensure compliance with HIPAA, HITECH, GDPR, and other relevant regulations Implement data encryption (at rest and in transit), masking, and access controls Architect systems for high availability, disaster recovery, and auditability Define and enforce data governance, retention, and audit logging policies Optimize database performance for large-scale healthcare datasets and real-time access Collaborate with security, compliance, and engineering teams to meet regulatory requirements Lead data migration and integration with EHR/EMR systems and third-party healthcare platforms Comply best practices for secure CI/CD pipelines involving database changes Monitor systems for data integrity, breaches, and anomalous access patterns Required Qualifications Bachelor’s or Master's degree in Computer Science, Information Systems, or related field 10+ years of progressive industry experience in enterprise technology, architecture, and systems management.7+ years of experience in database architecture, preferably in SaaS environments Prior experience building data pipelines using SSIS, Azure Data Factory or similarStrong experience with data lake architectures (e.g., AWS S3, Azure Data Lake, Google Cloud Storage) Proven experience designing or managing data farm / distributed data platforms (e.g., Hadoop, Spark, Databricks ecosystems) Hands-on experience handling sensitive data (PHI, PII/PPI) in regulated environments Strong knowledge of HIPAA compliance, data privacy, and security frameworks Expertise in relational databases (PostgreSQL, MySQL, SQL Server) and non-relational systems such as Cosmos DB, MongoDB Experience with cloud platforms (AWS, Azure, GCP), especially healthcare-compliant services Proficiency in data encryption, key management, and role-based access control (RBAC) Strong understanding of scaling strategies and distributed systems Must be legally authorized to work in the United States without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening. Preferred Qualifications Experience working with EHR/EMR systems (e.g., Epic, Cerner) or healthcare integrations (HL7, FHIR) Familiarity with healthcare data standards and interoperability frameworks Experience with audit logging, compliance reporting, and risk assessments Certifications such as AWS Certified Security Specialty, Certified HIPAA Professional (CHP) Experience with containerization (Docker, Kubernetes) Compensation and BenefitsThe salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:A choice of national medical and dental plans, and a national vision plan, including health incentive programsEmployee assistance and family support programs, including commuter benefits and tuition reimbursementAt least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policyRetirement and savings programs, such as our competitive 401(k) U.S. retirement savings planEmployees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discountFor more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Locations

  • USA, Indiana, Remote (Remote)
  • USA, Colorado, Remote (Remote)
  • USA, Kansas, Remote (Remote)
  • USA, Nevada, Remote (Remote)
  • USA, Utah, Remote (Remote)
  • USA, Arizona, Remote (Remote)
  • USA, Michigan, Remote (Remote)
  • USA, Ohio, Remote (Remote)
  • USA, Idaho, Remote (Remote)
  • USA, Tennessee, Remote (Remote)
  • USA, Pennsylvania, Remote (Remote)
  • USA, Wisconsin, Remote (Remote)
  • USA, North Carolina, Remote (Remote)
  • USA, Georgia, Remote (Remote)
  • USA, Texas, Remote (Remote)
  • USA, Oregon, Remote (Remote)

Skills Required

  • enterprise technologyintermediate
  • database architectureintermediate
  • data pipelines using SSISintermediate
  • data lake architecturesintermediate
  • HIPAA complianceintermediate
  • relational databasesintermediate
  • cloud platformsintermediate
  • data encryptionintermediate
  • healthcare data standardsintermediate
  • audit loggingintermediate
  • containerizationintermediate

Required Qualifications

  • Bachelor’s or Master's degree in Computer Science, Information Systems, or related field (degree in master)
  • 10+ years of progressive industry experience in enterprise technology, architecture, and systems management. (experience, 10 years)
  • Bachelor’s or Master's degree in Computer Science, Information Systems, or related field (degree in master)
  • 10+ years of progressive industry experience in enterprise technology, architecture, and systems management. (experience, 10 years)
  • 7+ years of experience in database architecture, preferably in SaaS environments (experience, 7 years)
  • 7+ years of experience in database architecture, preferably in SaaS environments (experience, 7 years)
  • Prior experience building data pipelines using SSIS, Azure Data Factory or similar (experience)
  • Strong experience with data lake architectures (e.g., AWS S3, Azure Data Lake, Google Cloud Storage) (experience)
  • Prior experience building data pipelines using SSIS, Azure Data Factory or similar (experience)
  • Strong experience with data lake architectures (e.g., AWS S3, Azure Data Lake, Google Cloud Storage) (experience)
  • Proven experience designing or managing data farm / distributed data platforms (e.g., Hadoop, Spark, Databricks ecosystems) (experience)
  • Proven experience designing or managing data farm / distributed data platforms (e.g., Hadoop, Spark, Databricks ecosystems) (experience)
  • Hands-on experience handling sensitive data (PHI, PII/PPI) in regulated environments (experience)
  • Hands-on experience handling sensitive data (PHI, PII/PPI) in regulated environments (experience)
  • Strong knowledge of HIPAA compliance, data privacy, and security frameworks (experience)
  • Strong knowledge of HIPAA compliance, data privacy, and security frameworks (experience)
  • Expertise in relational databases (PostgreSQL, MySQL, SQL Server) and non-relational systems such as Cosmos DB, MongoDB (experience)
  • Expertise in relational databases (PostgreSQL, MySQL, SQL Server) and non-relational systems such as Cosmos DB, MongoDB (experience)
  • Experience with cloud platforms (AWS, Azure, GCP), especially healthcare-compliant services (experience)
  • Experience with cloud platforms (AWS, Azure, GCP), especially healthcare-compliant services (experience)
  • Proficiency in data encryption, key management, and role-based access control (RBAC) (experience)
  • Proficiency in data encryption, key management, and role-based access control (RBAC) (experience)
  • Strong understanding of scaling strategies and distributed systems (experience)
  • Must be legally authorized to work in the United States without sponsorship. (experience)
  • Must be able to pass a comprehensive background check, which includes a drug screening. (experience)
  • Strong understanding of scaling strategies and distributed systems (experience)
  • Must be legally authorized to work in the United States without sponsorship. (experience)
  • Must be able to pass a comprehensive background check, which includes a drug screening. (experience)

Preferred Qualifications

  • Experience working with EHR/EMR systems (e.g., Epic, Cerner) or healthcare integrations (HL7, FHIR) (experience)
  • Experience working with EHR/EMR systems (e.g., Epic, Cerner) or healthcare integrations (HL7, FHIR) (experience)
  • Familiarity with healthcare data standards and interoperability frameworks (experience)
  • Familiarity with healthcare data standards and interoperability frameworks (experience)
  • Experience with audit logging, compliance reporting, and risk assessments (experience)
  • Experience with audit logging, compliance reporting, and risk assessments (experience)
  • Certifications such as AWS Certified Security Specialty, Certified HIPAA Professional (CHP) (certification)
  • Certifications such as AWS Certified Security Specialty, Certified HIPAA Professional (CHP) (certification)
  • Experience with containerization (Docker, Kubernetes) (experience)
  • Experience with containerization (Docker, Kubernetes) (experience)

Responsibilities

  • Design and implement secure, scalable, multi-tenant database architectures for healthcare SaaS applications
  • Design and implement secure, scalable, multi-tenant database architectures for healthcare SaaS applications
  • Develop data models and storage solutions for sensitive healthcare data (PHI, PII/PPI)
  • Develop data models and storage solutions for sensitive healthcare data (PHI, PII/PPI)
  • Ensure compliance with HIPAA, HITECH, GDPR, and other relevant regulations
  • Ensure compliance with HIPAA, HITECH, GDPR, and other relevant regulations
  • Implement data encryption (at rest and in transit), masking, and access controls
  • Implement data encryption (at rest and in transit), masking, and access controls
  • Architect systems for high availability, disaster recovery, and auditability
  • Architect systems for high availability, disaster recovery, and auditability
  • Define and enforce data governance, retention, and audit logging policies
  • Define and enforce data governance, retention, and audit logging policies
  • Optimize database performance for large-scale healthcare datasets and real-time access
  • Optimize database performance for large-scale healthcare datasets and real-time access
  • Collaborate with security, compliance, and engineering teams to meet regulatory requirements
  • Collaborate with security, compliance, and engineering teams to meet regulatory requirements
  • Lead data migration and integration with EHR/EMR systems and third-party healthcare platforms
  • Lead data migration and integration with EHR/EMR systems and third-party healthcare platforms
  • Comply best practices for secure CI/CD pipelines involving database changes
  • Comply best practices for secure CI/CD pipelines involving database changes
  • Monitor systems for data integrity, breaches, and anomalous access patterns
  • Monitor systems for data integrity, breaches, and anomalous access patterns

Benefits

  • general: This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
  • general: A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • general: Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • general: At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • general: Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • general: Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
  • general: A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • general: Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • general: At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • general: Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • general: Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
  • general: For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

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