Salesforce SOX Compliance & Release Manager (Hybrid in South San Francisco) Summary The Salesforce SOX Compliance & Release Manager will maintain and execute our Sarbanes-Oxley (SOX) and Information Technology General Controls (ITGC) frameworks across our enterprise Salesforce environment. This role will handle day-to-day audit support, access controls, and release coordination, and serve as an operational point of contact for Internal Audit, external auditors (EY), and cross-functional teams to ensure that change management policies and user lifecycle processes are consistently executed and documented. Core Responsibilities SOX & ITGC Operational Compliance Audit Support & Evidence Gathering: Assist in pulling walkthrough samples, change tickets, approval logs, and system evidence for external auditors (EY) and Internal Audit. Identity & Access Management (IAM): Process user access, role assignments, and timely deactivations in accordance with SLA metrics via Jira and ServiceNow. Access & Role Reviews: Perform scheduled quarterly and annual user access and profile audits to prevent Segregation of Duties (SoD) conflicts. Checklists & Documentation: Maintain operational compliance checklists, record change logs, and document system configurations for all Salesforce components and custom solutions. Focus on testing, monitoring, and evidencing control effectiveness for regulatory/SOX programs; strong fit for ITGC walkthroughs, sampling, documentation, and audit support. Release Coordination & Execution Release Logistics: Coordinate release schedules and deployment activities across Salesforce environments and connected integrations. Communication & Verification: Draft release notifications for cross-functional stakeholders and assist with post-production verification testing following system deployments. Ticket & Pipeline Tracking: Ensure all deployment requests in Jira/ServiceNow have appropriate change approvals, business sign-offs, and pre/post-deployment documentation attached before release. Key Qualifications Experience: 3 to 5 years of experience in program management, compliance support, audit execution and Salesforce administration within a regulated environment. Salesforce Knowledge: Hands-on experience with Salesforce user administration, profiles, permission sets, roles, and basic change management (Sandboxes, deployment steps). Process & Tooling Skills: Active experience using Jira or ServiceNow for ticket management, access controls, and release tracking. Audit Readiness: Familiarity with OTC and ITGC principles, SOX compliance concepts, and auditor evidence-gathering workflows. Education & Certifications: Bachelor’s degree in Information Systems, Business Administration, or related field. Preferred: Salesforce Certified Administrator Compliance & Regulatory > Compliance About Twist Bioscience Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA. At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers. Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.San Francisco Bay Area Pay Range$110,000—$132,500 USD