Job DescriptionGeneral Summary:The Manager Preclinical Research Strategy and Operations will play a critical role in driving operational excellence across the Preclinical Sciences organization. This position will partner closely with Procurement, Legal, Outsourced Contracting, Lab Operations, and Records Management to support business operations, improve processes, and enable efficient execution of departmental priorities.The ideal candidate is a highly organized and agile operations professional who thrives in a fast-paced environment, can manage multiple priorities simultaneously, and is experienced in supporting change management initiatives and driving efficiencies across cross-functional teams.Key Duties and Responsibilities:Partner with Research & Preclinical Sciences leadership to support strategic and operational initiatives across this multi-disciplinary departmentServe as a key liaison with Procurement, Legal, Outsourced Contracting, Business Continuity (Risk Management), Lab Operations, and Records Management to ensure smooth coordination of operational activitiesDrive end-to-end operational processes related to vendor engagement, contracting workflows via our outsourced environment documentation, and departmental supportIdentify opportunities to improve efficiency, streamline workflows, and enhance cross-functional collaborationSupport/lead change management activities associated with new processes, systems, tools, or organizational prioritiesTrack and help manage operational deliverables, timelines, dependencies, and action items across multiple stakeholdersAssist with vendor and contract-related processes in partnership with Procurement, Legal, and outsourced contracting teamsCollaborate with Lab Operations to support business continuity, operational planning, and process consistencyPartner with our CROs and our “Offsite Storage Management” to ensure appropriate handling, organization, and compliance of departmental documentation and recordsDevelop and maintain operational procedures, guidance documents, trackers, dashboards, and other tools to improve visibility and accountabilityFacilitate meetings, prepare status updates, and communicate operational progress, risks, and recommendations to leadershipProactively identify operational gaps and implement practical solutions to improve execution and scalabilitySupport departmental planning efforts and help align operational priorities with broader organizational goalsKnowledge and Skills:Cross-functional operational coordinationProcess improvement and workflow optimizationChange management leadershipVendor and contract process managementDocumentation and records management practicesMeeting facilitation and stakeholder communicationProject tracking and reportingMicrosoft Office Suite, including Excel, PowerPoint, Power BI, and WordExperience using digital tools, dashboards, or AI-assisted technologies to improve planning, documentation, communication, and operational efficiency.Data tracking, dashboards, and operational reporting toolsStandard operating procedures and business process documentationExperience in biotechnology, pharmaceutical, life sciences, or other regulated environmentsFamiliarity with procurement and legal review workflowsKnowledge of outsourced contracting processes and vendor managementExperience supporting laboratory or scientific operational functionsUnderstanding of records retention, compliance, and documentation standardsExperience with continuous improvement methodologiesAbility to navigate ambiguity and adapt quickly to evolving business needsStrong facilitation and stakeholder management skillsEducation and Experience:Bachelor’s degree in business, Life Sciences, Operations, or a related field5+ years of experience in strategic operations, business operations, project management, or a related functionExperience working cross-functionally with teams such as Research Scientists, Preclinical Project Managers, Procurement, Legal, Contracting, Lab Operations, or Records ManagementProven ability to manage multiple priorities and deliver results in a fast-paced, dynamic environmentExperience with Coupa, Icertis, Science ExchangeStrong organizational and project coordination skills with high attention to detailExperience supporting operational process improvement and change management initiativesExcellent written and verbal communication skillsPay Range:$124,000 - $186,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com