Job DescriptionGeneral Summary:The Senior Administrative Assistant will serve as a trusted administrative partner to the Vice President, U.S. Government Affairs & Patient Advocacy; the Vice President, Federal Government Affairs; and the Executive Director, State Government Affairs. The role is responsible for complex calendar and travel management, meeting and event coordination, contracting and invoice administration, executive preparedness, and broader team operations. The successful candidate will work with a high degree of independence, judgment, discretion, and attention to detail while managing competing priorities and interacting professionally with senior internal and external stakeholders. Key Duties and Responsibilities:Executive and Stakeholder SupportServe as a primary administrative point of contact for supported leaders, anticipating needs, applying sound judgment, and appropriately screening, routing, prioritizing, and escalating requests.Build effective working relationships with senior executives, administrative colleagues, external consultants, government officials and their staff, trade associations, patient advocacy organizations, vendors, and other stakeholders.Handle confidential, sensitive, and time-critical information with discretion and professionalism.Complex Calendar ManagementProactively manage complex and frequently changing calendars in Microsoft Outlook, including scheduling across multiple leaders, functions, sites, time zones, and external organizations.Resolve conflicts based on business priorities, protect time for critical work, and communicate scheduling tradeoffs and changes promptly.Ensure leaders have appropriate preparation time, meeting materials, locations, technology, and logistical information.Travel and Expense AdministrationUse Concur to independently arrange domestic and international travel, including air, ground transportation, lodging, itineraries, and other required logistics.Prepare and process accurate, timely expense reports and related correspondence; manage reimbursement inquiries and coordinate with travel agencies, airlines, hotels, and internal partners.Monitor and resolve time-sensitive travel and logistical issues during business travel, exercising judgment regarding when escalation is required.Contracting, Procurement, and InvoicingCoordinate the end-to-end administrative workflow for consultant and vendor agreements through Coupa and Icertis, including intake, routing, approvals, signatures, purchase orders, Statements of Work, invoicing, payment status, and record maintenance.Partner with Legal, Procurement, Finance, business owners, and external firms to support timely and compliant contracting and payment processes.Support vendor onboarding, invoice reconciliation, payment tracking, and basic departmental budget administration.Meetings, Conferences, and EventsPlan and coordinate recurring team meetings, leadership meetings, conferences, off-sites, dinners, and external engagements.Manage venue sourcing, attendee communications, catering, transportation, audiovisual and technology needs, vendor coordination, on-site logistics, contracts, payments, and expense reconciliation, as applicable; integrate with Corporate Services as needed.Coordinate activities in accordance with company meeting, expense, procurement, and compliance requirements.Executive Preparedness and Document SupportDevelop agendas, gather and distribute pre-read materials, maintain organized reference files, and track administrative follow-ups and action items.Support the preparation, proofreading, formatting, and distribution of presentations, correspondence, reports, and other business documents.Help ensure supported leaders are prepared for meetings, travel, and external engagements while appropriately distinguishing administrative support from substantive government affairs content ownership.Team and Department OperationsSupport recurring business routines, team communications, shared calendars and resources, distribution and contact lists, onboarding and offboarding, office access, technology, facilities, and supply needs.Lead or support administrative and operational projects requiring coordination across functions, vendors, and external organizations.Collaborate with administrative colleagues across the organization, share administrative best practices, and provide or receive backup coverage as needed.Records, Compliance, and Process ManagementMaintain accurate and organized business records in accordance with company policies and applicable document-retention requirements.Follow established requirements for contracting, procurement, expenses, external engagements, and information handling; identify and escalate potential process or compliance issues appropriately.Use Microsoft 365 and other enterprise platforms to improve organization, communication, document management, and administrative efficiencyKnowledge and Skills:Experience supporting multiple senior leaders, preferably at the Vice President level, in a complex and fast-paced organization.Experience in the biotechnology, pharmaceutical, healthcare, government affairs, public policy, or another highly regulated environment.Experience managing confidential matters and interacting with senior internal and external stakeholders.Experience with procurement, contracting, consultant or vendor administration, invoice workflows, and enterprise systems such as Concur, Coupa, and Icertis, or the ability to learn comparable platforms quickly.Advanced proficiency in Microsoft 365, including Outlook, Teams, Word, PowerPoint, and Excel, with strong document-formatting, proofreading, and written communication skills.Demonstrated ability to effectively leverage AI-enabled productivity tools (e.g., Microsoft Copilot and other approved enterprise technologies) to improve efficiency, enhance organization, streamline administrative processes, prepare meeting materials, conduct research, and support day-to-day business operations while exercising sound judgment and maintaining compliance with company policies.Proven ability to independently manage multiple projects and a high volume of daily work while maintaining accuracy, follow-through, and attention to detail.Strong judgment and problem-solving skills, including the ability to resolve non-routine issues, communicate conflicts and tradeoffs, and escalate matters appropriately.Excellent verbal, written, and interpersonal communication skills, with a highly professional and service-oriented approach.Ability to anticipate needs, adapt quickly to changing priorities, and remain composed and effective under pressure.Excellent organizational skills, initiative, accountability, and motivation.Education and Experience:Typically requires high school or secondary school educationTypically requires 2 years of administrative experience, or the equivalent combination of education and experiencePay Range:$39 - $58Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com