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Senior Director, Government Pricing

Vertex Pharmaceuticals

Senior Director, Government Pricing

full-timePosted: Aug 26, 2026Updated: Sep 1, 2026MA, Boston

Job Description

Job DescriptionGeneral Summary:The Senior Director, Government Pricing will lead the tactical, compliance, and strategic oversight of the Government Pricing and Transparency team. The team is comprised of complementary functions: Government Pricing Operations, Compliance, and State Price Transparency. This position will collaborate closely with the Managed Markets Specialty Pharmacy and Payer Field teams, Accounting, Legal, Finance, Global Information Systems, Government Affairs and Public Policy, OBIE, Treasury, Regulatory, Quality, and Pharmaceutical Operations. This role will demonstrate a level of detail, strategic understanding of Vertex business priorities, and executive presence.Key Duties and Responsibilities:Serve as subject matter expert on Government Pricing calculations, methodologies, reporting obligations and Bonafide Service Assessments.Oversees and approves all Government Pricing (AMP, BP, ASP, NonFAMP and 340B) calculations, documentation, and reasonable assumptions, ensuring accuracy and compliance to regulations.Leads analytics and scenario planning efforts that proactively evaluates changes to Government (Medicaid, FSS, Medicare and 340B) programs considerations for in-line and launch productsSupportcontract development efforts and collaborate with business partners with contract negotiations; ensures operational viability of rebate and payment processes contemplated by contract terms.Oversee state price transparency reportingTracks state regulations and forecast assumptions; measures financial impacts to GTNPartners with GIS to ensure timely and compliant upgrades to Revitas modules.Sponsors or leads complex, cross-functional initiativesLeads, mentors, and develops team members to strengthen team expertise and performanceLead and oversees external audits and SOX compliance activitiesLead and support implementation of regulatory changesPartner with legal and compliance to ensure operational alignment with current regulatory requirements.Oversee Bona Fide Service Fee assessments.Knowledge and Skills:Experience with forecasting, modeling and estimation of financial impacts to GTNDemonstrated knowledge of US payer landscape and public policy developmentsStrong written, communication and presentation skillsExperience leading people/teams with excellent cross-functional leadership and collaboration skillsExperience in leading contracting strategy, contract management and contract operations a plusAdvanced understanding of commercial and government payersFamiliarity with distributors, 3PLs, limited distribution networks and specialty productsDedication to cross-functional partnership and building/maintaining positive relationships across teamsFamiliarity with distribution practices in assigned geographic region(s)An advanced understanding of FSS and CMS statutory programs and price calculations (NFAMP, IFF, AMP, BP, URA), State Price Reporting requirements, the 340B Program, Coverage Gap Discount Program and Tricare.Familiarity with chargebacks processes and membership managementExperience with Revitas or Model N systemsKnowledge of GXPEducation and Experience:Bachelor's degree required12+ years of professional experience in pharma/biotech industry/ relevant consulting environment, including 5 years of supervisory/management experience, or the equivalent combination of education and experiencePay Range:$232,000 - $348,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Locations

  • MA, Boston

Salary

232,000 - 348,000 USD / yearly

Responsibilities

  • Serve as subject matter expert on Government Pricing calculations, methodologies, reporting obligations and Bonafide Service Assessments.
  • Oversees and approves all Government Pricing (AMP, BP, ASP, NonFAMP and 340B) calculations, documentation, and reasonable assumptions, ensuring accuracy and compliance to regulations.
  • Leads analytics and scenario planning efforts that proactively evaluates changes to Government (Medicaid, FSS, Medicare and 340B) programs considerations for in-line and launch products
  • Supportcontract development efforts and collaborate with business partners with contract negotiations; ensures operational viability of rebate and payment processes contemplated by contract terms.
  • Oversee state price transparency reporting
  • Tracks state regulations and forecast assumptions; measures financial impacts to GTN
  • Partners with GIS to ensure timely and compliant upgrades to Revitas modules.
  • Sponsors or leads complex, cross-functional initiatives
  • Leads, mentors, and develops team members to strengthen team expertise and performance
  • Lead and oversees external audits and SOX compliance activities
  • Lead and support implementation of regulatory changes
  • Partner with legal and compliance to ensure operational alignment with current regulatory requirements.
  • Oversee Bona Fide Service Fee assessments.

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